Mutation of worm gene, swip-10, triggers age-dependent death of dopamine neurons

(Florida Atlantic University) Looking at dopamine neurons in a tiny worm's brain, scientists have identified a novel pathway that sustains the health of these cells. The normal actions of swip-10 to protect dopamine neurons are indirect, derived from the gene's action in support cells called glia, adjacent to the dopamine neurons. Glial cells are known to play a critical role in shaping neuronal development, structure, and function, but, this study offers a clear demonstration that they also kee...